Pushapagiri, formerly known as Cherupushpagiri was the first official residence or Aramana of His Lordship Late Jacob Mar Theophilos of happy memory, the chief collaborator with the Servant of God, Geevarghese Mar Ivanios for the cause of Reunion and Catholic Communion in Malankara. Moved by the health situation of women in pregnancy and new born children in Travancore, His Excellency zacharias Mar Athanasios, the third Bishop of the Archdiocese of Tiruvalla started a clinic which later turned to be a centre for training girls, especially nurses.

The strength and vitality of this institution is nothing but the spiritual foundation laid by this great prelate Mar Theophilos. This was a historic moment in the history of Travancore that made manifold changes in the lives of families and in health care system. Due to the blessings of the Lord and especially through the intercession of the Blessed Mother and St. Therese of Lisieux and through the hard work of the priests and doctors and nurses and other staff, Pushpagiri has grown to be one of the best Medical Institutes in Kerala.

Recently it has bagged the 10th position in health research in the world, especially in the field of Endocrinology. It is one of the premier institutions of the Syro-Malankara Catholic Church and is committed to health care with uncompromising services and medical education and training of health personnel with quality and commitment, who are ethically upright and scientifically motivated.